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Four North Carolina patients at a single hospital tested positive for a type of swine flu that is resistant to Tamiflu, health officials said Friday. The cases reported at Duke University Medical Center over six weeks make up the biggest cluster seen so far in the U.S. Tamiflu -- made by Switzerland's Roche Group -- is one of two flu medicines that help against swine flu, and health officials have been closely watching for signs that the virus is mutating, making the drugs ineffective.
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